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Christopher R Chapple Selected Research

Overactive Urinary Bladder (Overactive Bladder)

1/2022Corrigendum re "Multicriteria Decision Analysis Applied to the Clinical Use of Pharmacotherapy for Overactive Bladder Symptom Complex" [Eur Urol Focus 2020;6:522-30].
9/2021Contemporary Outcomes of Surgery for Primary and Recurrent Genitourinary Fistulae in a Well-resourced Country.
1/2020Multicriteria Decision Analysis Applied to the Clinical Use of Pharmacotherapy for Overactive Bladder Symptom Complex.
1/2020Safety and Efficacy of Mirabegron: Analysis of a Large Integrated Clinical Trial Database of Patients with Overactive Bladder Receiving Mirabegron, Antimuscarinics, or Placebo.
6/2018A strategy utilizing ambulatory monitoring and home and clinic blood pressure measurements to optimize the safety evaluation of noncardiovascular drugs with potential for hemodynamic effects: a report from the SYNERGY trial.
1/2018Editorial Comment from Dr Chapple to Long-term safety and efficacy of the novel β3 -adrenoreceptor agonist vibegron in Japanese patients with overactive bladder: A phase III prospective study.
12/2017Efficacy and safety of daily mirabegron 50 mg in male patients with overactive bladder: a critical analysis of five phase III studies.
12/2017Botulinum Toxin Versus Neural Stimulation.
11/2017Comparative assessment of the efficacy of onabotulinumtoxinA and oral therapies (anticholinergics and mirabegron) for overactive bladder: a systematic review and network meta-analysis.
10/2017Efficacy and safety of combinations of mirabegron and solifenacin compared with monotherapy and placebo in patients with overactive bladder (SYNERGY study).
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Christopher R Chapple Research Topics

Disease

46Overactive Urinary Bladder (Overactive Bladder)
01/2022 - 01/2002
16Stress Urinary Incontinence
09/2021 - 07/2003
16Lower Urinary Tract Symptoms
01/2017 - 09/2004
10Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2017 - 01/2004
7Pain (Aches)
09/2021 - 02/2007
7Urinary Incontinence
01/2019 - 07/2006
5Pelvic Organ Prolapse
01/2020 - 01/2012
5Nocturia
10/2017 - 11/2004
4Prostatic Neoplasms (Prostate Cancer)
12/2021 - 08/2008
4Urinary Tract Infections (Urinary Tract Infection)
10/2021 - 01/2014
4Urethral Stricture
01/2021 - 04/2015
4Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
12/2019 - 04/2006
4Urinary Retention
10/2017 - 02/2005
4Constipation
10/2017 - 11/2002
3Pathologic Constriction (Stenosis)
04/2018 - 09/2008
3Dizziness (Lightheadedness)
05/2015 - 08/2013
3Orthostatic Hypotension (Postural Hypotension)
05/2015 - 01/2005
3Urge Urinary Incontinence (Urge Incontinence)
07/2005 - 11/2002
2Underactive Urinary Bladder
01/2022 - 01/2018
2Interstitial Cystitis (Interstitial Cystitis, Chronic)
07/2021 - 10/2007
2Inflammation (Inflammations)
01/2020 - 10/2013
2Retrograde Ejaculation
12/2019 - 05/2015
2Neoplasms (Cancer)
08/2019 - 01/2019
2Spinal Cord Injuries (Spinal Cord Injury)
03/2019 - 11/2002
2Tachycardia (Tachyarrhythmias)
05/2017 - 11/2002
2Hypertension (High Blood Pressure)
05/2017 - 01/2014
2Infections
05/2015 - 07/2014
1Hemorrhage
10/2021
1Pruritus (Itching)
10/2021
1Spasm (Spasms)
01/2020
1Asymptomatic Infections
01/2020
1Edema (Dropsy)
12/2019
1Congenital Abnormalities (Deformity)
09/2019
1Sneezing
01/2019
1Sexually Transmitted Diseases (Sexually Transmitted Disease)
01/2019
1Fatigue
01/2019
1Dyspepsia (Indigestion)
10/2017
1Fistula
01/2016

Drug/Important Bio-Agent (IBA)

17Muscarinic AntagonistsIBA
01/2020 - 11/2002
15mirabegronIBA
01/2020 - 02/2013
9Solifenacin SuccinateFDA Link
01/2019 - 01/2005
5Pharmaceutical PreparationsIBA
01/2020 - 07/2005
5Botulinum Toxins (Botulinum Toxin)IBA
01/2020 - 07/2006
5silodosinFDA Link
05/2015 - 03/2011
5Tolterodine Tartrate (Detrol)FDA Link
11/2010 - 01/2002
4Prostate-Specific Antigen (Semenogelase)IBA
12/2021 - 01/2004
4Cholinergic Agents (Cholinergics)IBA
04/2014 - 11/2004
3Adrenergic Receptors (Adrenergic Receptor)IBA
06/2018 - 04/2014
3Type A Botulinum Toxins (Botox)FDA Link
11/2017 - 08/2013
3Cholinergic Antagonists (Anticholinergics)IBA
11/2017 - 11/2002
3Tamsulosin (Flomax)FDA LinkGeneric
03/2011 - 01/2005
3Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
08/2008 - 11/2002
2Biological ProductsIBA
01/2020 - 05/2015
2Anti-Bacterial Agents (Antibiotics)IBA
01/2020 - 07/2014
2Polypropylenes (Polypropylene)IBA
01/2019 - 01/2019
2oxybutynin (Tavor)FDA LinkGeneric
07/2009 - 01/2002
2Adenosine Triphosphate (ATP)IBA
10/2007 - 10/2002
2darifenacinFDA Link
11/2004 - 11/2002
1Muscarinic M3 ReceptorIBA
01/2022
1TamoxifenFDA LinkGeneric
10/2021
1Captopril (Capoten)FDA LinkGeneric
10/2021
1SteroidsIBA
10/2021
1A-factor (Streptomyces)IBA
01/2020
1HolmiumIBA
12/2019
1potassium titanylphosphateIBA
12/2019
1Mineral Oil (Liquid Paraffin)FDA LinkGeneric
09/2019
1Biomarkers (Surrogate Marker)IBA
08/2019
1HydrogelsIBA
01/2019
1Biocompatible Materials (Biomaterials)IBA
01/2019
1Estradiol (Delestrogen)FDA LinkGeneric
01/2019
1Mitomycin (Mitomycin-C)FDA LinkGeneric
12/2018
1CollagenIBA
04/2018
1N- (4- ((5- (hydroxy(phenyl)methyl)pyrrolidin- 2- yl)methyl)phenyl)- 4- oxo- 4,6,7,8- tetrahydropyrrolo(1,2- a)pyrimidine- 6- carboxamideIBA
01/2018
1Dihydrotachysterol (AT 10)IBA
01/2017
1Phosphodiesterase InhibitorsIBA
08/2016
1Midazolam (Versed)FDA LinkGeneric
01/2016
1Therapeutic UsesIBA
02/2015

Therapy/Procedure

28Therapeutics
01/2021 - 11/2002
10Drug Therapy (Chemotherapy)
01/2022 - 01/2004
5Suburethral Slings (Tension-Free Vaginal Tape)
10/2017 - 07/2003
4Cystectomy
09/2021 - 03/2006
2Catheters
01/2020 - 02/2005
2Transurethral Resection of Prostate (TURP)
12/2019 - 10/2015
2Injections
07/2015 - 08/2008
1Bathroom Equipment
01/2020
1Aftercare (After-Treatment)
01/2020
1Indwelling Catheters (Indwelling Catheter)
01/2020
1Surgical Mesh
01/2020
1Electrocoagulation (Electrocautery)
12/2019
1Solid-State Lasers
12/2019
1Semiconductor Lasers
12/2019
1Combined Modality Therapy
08/2019
1Laminectomy
03/2019
1Transplantation
03/2019
1Radiotherapy
01/2019
1Bioreactors (Bioreactor)
01/2019
1Massage (Zone Therapy)
07/2015
1Transjugular Intrahepatic Portasystemic Shunt
04/2015
1Transcutaneous Electric Nerve Stimulation (TENS)
04/2015
1Sutures (Suture)
04/2015